Drug intelligence / Profile preview

REC610

Development stage
Phase 1
Lead developer
Recbio
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

**REC610** is an investigational, novel-adjuvanted recombinant protein-subunit vaccine developed by Recbio to prevent herpes zoster in adults aged 40 years and older. It contains recombinant varicella-zoster virus glycoprotein E produced in CHO cells and uses Recbio's BFA01 adjuvant to enhance gE-specific CD4-positive T-cell and antibody responses. REC610 is administered as a two-dose intramuscular regimen. Its Phase III China program enrolled 24,640 adults; the company completed vaccination and submitted a marketing application to China's NMPA, which was accepted in December 2025. ([recbio.cn](https://www.recbio.cn/en/pipeline/pipeline/shingles/rec610/))

Other names
recombinant zoster vaccine CHO cell
02

Targets

gE (VZV glycoprotein E)

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