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Receptor Modulator
- Development stage
- Preclinical
- Lead developer
- Saccharo
- Modality
- Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Small Molecules
01
Overview
Receptor Modulator is a preclinical-stage therapeutic program being developed by Saccharo, utilizing their proprietary anti-dPSA platform. The program focuses on modulating immune cell activity through the dual targeting of de-N-acetyl-polysialic acid (dPSA) and Siglec receptors. It employs both small molecule and engineered antibody fragment (eFab) modalities. The mechanism of action allows for the potential activation or inhibition of immune responses, providing a broad therapeutic scope that includes autoimmune diseases, oncology, and infectious diseases. As of the latest pipeline information, the program is in the lead optimization phase.
- Other names
- Receptor Modulator
02
Targets
dPSA (de-N-acetyl-polysialic acid)Siglec (Siglec family)
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