Drug intelligence / Profile preview

recNY-ESO-1 + AS15

Development stage
Unknown
Lead developer
GSK
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

recNY-ESO-1 + AS15 is an antigen-specific cancer immunotherapeutic vaccine composed of recombinant NY-ESO-1 protein (recNY-ESO-1), a well-characterized cancer-testis antigen, combined with the immune adjuvant AS15. The vaccine is designed to induce and amplify immune responses (both humoral and cellular) against tumors expressing the NY-ESO-1 antigen. It is intended for patients whose tumors are positive for NY-ESO-1, such as a subset of metastatic cutaneous melanoma, aiming to boost the body's immune system to recognize and attack cancer cells. Clinical evaluation has focused on safety and immunogenicity in advanced melanoma patients[2][3][4].

Brand names
NY-ESO-1 Antigen-Specific Cancer ImmunotherapeuticNY-ESO1 Antigen-Specific Cancer ImmunotherapeuticNY-ESO 1 Antigen-Specific Cancer Immunotherapeutic
Other names
NY-ESO-1 ASCINY-ESO1 ASCINY-ESO 1 ASCI
02

Targets

NY-ESO-1 (New york esophageal squamous cell carcinoma 1)

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