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recombinant Adenoviral Interferon α2b
- Development stage
- Unknown
- Lead developer
- Ferring Pharmaceuticals
- Modality
- Recombinant Proteins and Enzymes, Gene Therapies
- Administration
- Intravesical
01
Overview
Recombinant Adenoviral Interferon α2b (Ad-IFN) is a gene therapy that utilizes a recombinant adenovirus to deliver the gene encoding interferon α2b. This leads to the production of interferon-alpha (IFNα) in the target tissue. It is formulated with the excipient Syn3 and has been investigated for intravesical administration in nonmuscle invasive bladder cancer.
- Other names
- adenoviral interferoninterferon-alpha
02
Targets
IFNAR2 (Interferon alpha/beta receptor subunit 2)IFNAR (Immune system modulation via type I interferon receptor)
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