Drug intelligence / Profile preview

recombinant bovine basic fibroblast growth factor gel

Development stage
Phase 4
Lead developer
Zhuhai Essex Bio-Pharmaceutical
Modality
Recombinant Proteins and Enzymes
Administration
Ophthalmic, Topical
01

Overview

Recombinant bovine basic fibroblast growth factor (rb-bFGF) gel is a recombinant protein therapeutic developed by Zhuhai Essex Bio-Pharmaceutical. It is formulated as a topical or ophthalmic gel to promote tissue repair and wound healing. The active ingredient, rb-bFGF, is a multifunctional growth factor that binds to fibroblast growth factor receptors (FGFRs) on target cells, stimulating cell division, proliferation, migration, and differentiation of ectoderm- and mesoderm-derived cells (such as epithelial cells, fibroblasts, and vascular endothelial cells). It is approved in China under the brand names Beifuxin (for body surface wounds, burns, and surgical incisions) and Beifushu (as an eye gel for corneal damage and dry eye disease).

Brand names
Beifushu Eye GelBeifuxinBeifuxin Gel
Other names
rb-bFGF gelrecombinant bovine basic fibroblast growth factor eye gelrecombinant bovine basic fibroblast growth factor ophthalmic gelrecombinant bovine bFGF gelrecombinant bovine fibroblast growth factor-basic gelrecombinant cattle basic fibroblast growth factor gel
02

Targets

FGFR1 (Fibroblast growth factor receptor 1)FGFR2 (Keratinocyte growth factor receptor)FGFR3 (Fibroblast growth factor receptor 3)FGFR4 (Fibroblast growth factor receptor 4)

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