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The recombinant COVID-19 trivalent protein vaccine is a next-generation, subunit-based SARS-CoV-2 vaccine candidate designed to provide broad protection against multiple circulating variants of concern. It contains three distinct spike proteins representing the XBB, BA.5, and Delta variants of SARS-CoV-2, produced using a baculovirus expression system in Sf9 insect cells[5]. The formulation is intended for use as a booster in adults aged 18 years and older and aims to elicit robust humoral and cellular immune responses against these major viral lineages. This approach leverages the safety profile of traditional subunit vaccines while targeting evolving viral threats through multivalency.
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