recombinant follicle stimulating hormone + gonadotropin releasing hormone agonist

This is a **combination drug** composed of recombinant follicle stimulating hormone (rFSH) and a gonadotropin releasing hormone (GnRH) agonist. rFSH is a recombinant protein that stimulates the growth and maturation of ovarian follicles in women and supports spermatogenesis in men, primarily by activating FSH receptors on granulosa or Sertoli cells. GnRH agonists act on the pituitary GnRH receptor to initially stimulate and then downregulate luteinizing hormone (LH) and FSH release, allowing for controlled ovarian stimulation during fertility treatments. This combination is primarily used in assisted reproductive technology protocols such as in vitro fertilization (IVF) to optimize follicular development, control the timing of ovulation, and potentially improve pregnancy and live birth rates[3][5].