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Recombinant Hepatitis B Vaccine (CHO)

Development stage: Unknown
Lead developer: NCPC GeneTech Biotechnology
Modality: Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

The Recombinant Hepatitis B Vaccine (CHO) is a biologic vaccine developed and manufactured by NCPC GeneTech (North China Pharmaceutical Genetech Biotechnology Co., Ltd.). It is produced using a recombinant DNA platform where Chinese hamster ovary (CHO) cells express the hepatitis B surface antigen (HBsAg). The purified antigen is formulated with an aluminum hydroxide adjuvant to enhance immunogenicity. Upon intramuscular injection, the vaccine stimulates the host's immune system to produce specific anti-HBs antibodies, providing active immunity against infection by all known subtypes of the hepatitis B virus. It is approved in China for use in both pediatric and adult populations as part of standard immunization schedules.

Brand names: 重组乙型肝炎疫苗(CHO)
Other names: Hepatitis B vaccineRecombinant HBsAg vaccine (CHO)NCPC GeneTech Hepatitis B vaccine

Targets

HBsAg (Hepatitis B surface antigen)

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