recombinant human collagen hydrogel

Recombinant human collagen hydrogel is a biomaterial composed of laboratory-produced (recombinant) human collagen proteins formulated into a three-dimensional, water-rich gel. These hydrogels are engineered to mimic the natural extracellular matrix and provide structural support for tissue regeneration. They promote wound healing by stimulating cell proliferation, migration, angiogenesis (formation of new blood vessels), and enhanced deposition of native collagen[1][2][6]. Recombinant technology allows for high purity and batch-to-batch consistency compared to animal-derived collagens[4]. The hydrogels can be tailored with different types of recombinant human collagens (such as type I or III) and may be combined with other bioactive components or cells. Mechanistically, they act as scaffolds that facilitate tissue repair and can also serve as "sponges" to absorb toxic metabolites such as methylglyoxal after myocardial infarction[3]. Applications include chronic wound care (e.g., diabetic ulcers), skin injury repair, cardiac tissue regeneration post-myocardial infarction, and broader uses in regenerative medicine[1][3][5][6].

Brand names

VECOLLAN

Other names

recombinant human collagen hydrogelrhCol hydrogelrecombinant humanized collagen hydrogelrhCol III-CS hydrogel