Drug intelligence / Profile preview

recombinant human interferon chimera

Development stage
Preclinical
Lead developer
Heligenics
Modality
Recombinant Proteins and Enzymes
01

Overview

Recombinant human interferon chimera is a protein-based therapeutic candidate being developed by Heligenics. It is designed as a dual gene agonist targeting the interferon-alpha2 receptor (IFNAR). The drug is engineered as a chimeric protein to optimize interferon signaling pathways, potentially offering improved efficacy and safety profiles compared to standard interferon-alpha treatments. It is currently in the lead validation (preclinical) stage for the treatment of acute myeloid leukemia (AML), squamous cell carcinoma, polycythemia vera, and various viral infections.

Other names
Recombinant Human Interferon Chimeras
02

Targets

IFNAR (Immune system modulation via type I interferon receptor)IFNAR2 (Interferon alpha/beta receptor subunit 2)

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