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recombinant meningococcal group b vaccine
- Development stage
- Approved
- Lead developer
- GSK
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Recombinant meningococcal group B vaccine is an investigational prophylactic vaccine candidate developed by Beijing Zhifei Lvzhu Biopharmaceutical for prevention of disease caused by *Neisseria meningitidis* serogroup B. The candidate is produced using an *Escherichia coli* expression system and has been evaluated in a randomized, double-blind, placebo-controlled Phase 1 study in participants aged 3 months to 50 years to assess safety, tolerability, and preliminary immunogenicity. ([synapse.patsnap.com](https://synapse.patsnap.com/drug/ce426554000842929d87091b39739a1e))
- Other names
- recombinant meningococcal group b vaccine e. colirecombinant group b meningococcal vaccine e. coli
02
Targets
PorA (Major outer membrane protein PorA)fHbp (Factor H-binding protein)NadA (Neisserial adhesin A)NHBA (Neisserial heparin-binding antigen)CFH (Complement factor H)
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