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Recombinant Mouse FGL2, also known as Fibroleukin, is a 64-70 kDa secreted glycoprotein of the Fibrinogen-like superfamily. It has prothrombinase activity, which requires calcium and acidic phospholipids, and promotes T regulatory (Treg) activity by suppressing DC, T, and B cell immune reactivity. FGL2 is involved in various biological processes, including coagulation, immune regulation, and may play roles in conditions like autoimmune glomerulonephritis and tumor progression.
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