Drug intelligence / Profile preview

recombinant novel coronavirus XBB.1.5 variant vaccine

Development stage
Phase 3
Lead developer
CanSino Biologics
Modality
Vaccines & Immunotherapeutics, Viral Vectors → Gene Addition/Replacement → Gene Therapies
Administration
Inhalation
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Overview

Recombinant novel coronavirus XBB.1.5 variant vaccine is a viral vector vaccine designed to protect against COVID-19 caused by the SARS-CoV-2 XBB.1.5 variant. The specific version described in clinical trials (such as ChiCTR2300075626) utilizes a replication-defective adenovirus type 5 (Ad5) vector to deliver the genetic sequence of the XBB.1.5 spike protein. Developed by CanSino Biologics in collaboration with the Seventh Medical Center of PLA General Hospital, this vaccine is formulated for administration via inhalation. This route is intended to elicit mucosal immunity in the respiratory tract—the primary site of viral entry—in addition to systemic humoral and cellular immune responses. It is primarily positioned as a booster dose for adults who have previously completed a primary vaccination series.

Brand names
Convidecia Air
Other names
recombinant novel coronavirus XBB.1.5 variant vaccine (adenovirus type 5 vector)inhaled Ad5-vectored XBB.1.5 COVID-19 vaccine
02

Targets

SARS-CoV-2 spike

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