Drug intelligence / Profile preview

recombinant novel coronavirus XBB.1.5 variant vaccine (type 5 adenovirus vector)

Development stage
Unknown
Lead developer
CanSino Biologics
Modality
Adenoviral Vectors → Other Viral Vectors → Viral Vectors → Gene Addition/Replacement → Gene Therapies, Vaccines & Immunotherapeutics
Administration
Intramuscular Injection
01

Overview

A recombinant COVID-19 vaccine targeting the SARS-CoV-2 Omicron subvariant XBB.1.5, using a type 5 adenovirus vector to deliver the spike protein antigen of the virus to induce immune responses. This non-replicating viral vector vaccine expresses the spike protein of the XBB.1.5 variant, aiming to stimulate broad-spectrum neutralizing antibodies and T cell responses against this highly immune-evasive and transmissible Omicron subvariant and related variants of concern[1][2][3]. The vaccine is designed to overcome immune resistance caused by mutations in receptor-binding domain regions of emerging variants[1]. It is developed as part of efforts for universal protection against evolving SARS-CoV-2 Omicron strains.

Other names
重组新型冠状病毒XBB.1.5变异株疫苗(5型腺病毒载体)
02

Targets

SARS-CoV-2 spike

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