Drug intelligence / Profile preview

recombinant protein + Advax

Development stage
Unknown
Lead developer
Vaxine
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

recombinant protein + Advax refers to a vaccine platform developed by Vaxine that combines recombinant protein antigens with the proprietary Advax adjuvant. Advax is a non-inflammatory adjuvant derived from delta-inulin designed to enhance both humoral and cellular immune responses, specifically targeting Th1 and Th17 pathways which are critical for protection against intracellular pathogens. This platform is applied to several candidates in Vaxine's pipeline, most notably a tuberculosis vaccine (currently in IND-enabling studies) targeting Mycobacterium tuberculosis antigens, and an Alzheimer's disease vaccine (in Phase 1) targeting amyloid and tau proteins. Other preclinical applications include vaccines for Shigellosis and Zika virus infection. The platform is intended to provide robust immunogenicity without the high reactogenicity often associated with traditional adjuvants.

Other names
recombinant protein + Advax TB vaccinerecombinant protein + Advax Shigella vaccinerecombinant protein + Advax Alzheimer's vaccinerecombinant protein + Advax Zika vaccine
02

Targets

4R tau (Microtubule-associated protein tau (cis-pT231 conformation))S. flexneri LPS (Shigella flexneri lipopolysaccharide)Aβ (Amyloid-beta pathological forms)ZIKV E (Zika virus envelope protein)TLR9 (Toll-like receptor 9)pE-Aβ (Pyroglutamylated amyloid-β)

Beyond the preview

Go deeper on recombinant protein + Advax.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on recombinant protein + Advax.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call