Drug intelligence / Profile preview

recombinant timothy grass pollen allergen cocktail

Development stage
Phase 3
Lead developer
Biomay
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

Recombinant timothy grass pollen allergen cocktail is an allergen extract immunotherapy composed of a mixture (cocktail) of recombinant major allergens from timothy grass (Phleum pratense) pollen. It is designed to induce immune tolerance in individuals with IgE-mediated allergic rhinitis (hay fever) and rhinoconjunctivitis caused by grass pollen. The recombinant allergens act primarily as immunomodulators, aiming to safely desensitize patients by promoting protective immune responses (including blocking antibodies) and reducing allergic symptoms. This approach improves safety and consistency compared to natural extracts. The developer includes Biomay AG, and clinical studies have tested this cocktail in combination with aluminium hydroxide as an adjuvant for subcutaneous immunotherapy in patients with grass pollen allergies[2].

Other names
recombinant timothy grass pollen allergoidsrecombinant timothy grass pollen allergen cocktailhigh-dose rPhleumrPhleum
02

Targets

Group 5 grass pollen allergenPhl p (Timothy grass pollen allergen)EXPB1 (Group 1 beta-expansin)Phl p 6 (Timothy grass pollen allergen Phl p 6)

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