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Recosulin is a branded family of insulin formulations, including injectable human insulin (short‑acting regular insulin, intermediate‑acting NPH insulin, and biphasic premixes of soluble and isophane insulin) and an oral buccal insulin spray, used for glycemic control in adults and children with type 1 and type 2 diabetes mellitus. Injectable Recosulin products act by binding to insulin receptors on target tissues such as liver, muscle, and adipose tissue, promoting glucose uptake, inhibiting hepatic glucose production, and modulating lipid and protein metabolism, with regular insulin providing rapid prandial control and NPH or premixed formulations providing basal or biphasic profiles. The oral buccal spray formulation, marketed as Oral Recosulin in India, delivers human insulin via absorption through the buccal mucosa using a specialized device, aiming to provide a needle‑free alternative for prandial insulin therapy while avoiding pulmonary deposition.[2][5][8][10][13][17][19]
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