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DEX-Rectal is a plain rectal suppository formulation of dexmedetomidine, a selective alpha-2 adrenergic receptor agonist. It is being evaluated by Assiut University in a Phase 2/3 clinical trial (NCT05340725) as an active comparator against rectal dexmedetomidine niosomes (DEX-Nano-Rectal) and intravenous dexmedetomidine (DEX-IV) for postoperative analgesia in pediatric cancer patients undergoing bone marrow biopsy and aspiration procedures.
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