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red raspberry leaf extract
- Development stage
- Preclinical
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- Oral
01
Overview
Red raspberry leaf extract is a botanical dietary supplement being investigated for its potential role in weight management. Its proposed mechanism of action involves the inhibition of two key enzymes: Diacylglycerol acyltransferase-1 (DGAT-1) and ghrelin O-acyltransferase (GOAT). Inhibition of DGAT-1 is hypothesized to reduce the re-esterification of dietary fats into circulating triglycerides, potentially leading to decreased fat deposition. Inhibition of GOAT aims to prevent the activation of ghrelin, a hormone that stimulates appetite, thereby potentially diminishing food intake and lipid storage. This extract is being studied for its effects on appetite and fat metabolism in healthy, overweight, and obese individuals.
- Other names
- raspberry leafred raspberry leaf extractRubus idaeus leaf extractRubus idaeusRubus strigosusRubi idaei folium
02
Targets
DGAT1 (Diacylglycerol O-acyltransferase 1)GOAT (Ghrelin O-acyltransferase)
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