Refcon Advance

Refcon Advance is an oral suspension developed and manufactured by the Turkish pharmaceutical company Vefa İlaç. It is classified as a reflux suppressant and contains a combination of 100 mg sodium alginate and 20 mg potassium bicarbonate per milliliter. The drug is indicated for the treatment of symptoms associated with gastroesophageal reflux disease (GERD), including heartburn, acid regurgitation, and indigestion, particularly those occurring after meals or during pregnancy. Its mechanism of action is primarily physical; upon ingestion, the sodium alginate reacts with gastric acid to form a viscous alginic acid gel raft that floats on the stomach contents. The potassium bicarbonate reacts with the acid to release carbon dioxide, which becomes trapped in the gel raft, increasing its buoyancy. This raft acts as a physical barrier to prevent the reflux of gastric acid into the esophagus.

Brand names

Refcon Advance

Other names

Refcon Advance (200 ml)