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**Reference cream 1 (RC1)** is an anonymized topical emollient comparator used in the RESTORE Study Phase 1, a single-application study in adults with dry, atopic dermatitis-prone skin. It was one of three commonly prescribed UK reference creams evaluated against ceramide-containing multi-vesicular-emulsion test products. The publication does not disclose a commercial product name, manufacturer, or ingredient composition for RC1; therefore, it cannot be resolved to a unique marketed medicine or defined active substance.
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