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Reference0912 is an ophthalmic drug formulation developed as eye drops for the treatment of open angle glaucoma and ocular hypertension. It was used as a comparator in clinical trials against SPARC0912, which contains a similar active ingredient but with a different preservative. The precise active ingredient and mechanism of action for Reference0912 are not specified in the available sources, but it is likely to be a standard-of-care agent for lowering intraocular pressure, such as a prostaglandin analog or beta-blocker, given its use in glaucoma and ocular hypertension studies[1][2]. The product was evaluated in phase 3 clinical trials.
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