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RegenoGel
- Development stage
- Phase 4
- Lead developer
- ProCore Bio
- Modality
- Recombinant Proteins and Enzymes, Hydrogel Systems → Drug Delivery Systems
- Administration
- Intraarticular
01
Overview
RegenoGel is a novel intra-articular viscosupplement and regenerative scaffold developed by ProCore Ltd for the treatment of knee osteoarthritis. It consists of high molecular-weight hyaluronic acid (HA) chemically conjugated to fibrinogen using the proprietary HaProlink technology. Upon injection into the joint and activation by thrombin or tissue factors, the conjugate assembles into a solid, insoluble fibrin-HA hydrogel. This hydrogel provides mechanical protection, enhances viscosupplementation, and serves as a bioactive scaffold to promote stem cell attachment and tissue regeneration. The product exists in two forms: RegenoGel, which utilizes purified human plasma-derived fibrinogen, and RegenoGel-OSP, which utilizes autologous plasma-derived fibrinogen.
- Brand names
- RegenoGel
- Other names
- RegenoGel-OSPfibrin-hyaluronan hydrogelfibrin-HA conjugate
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