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Rejuvxl (AION-301) is an immunomodulatory cell therapy being developed by AION Healthspan. It utilizes mesenchymal stromal cells (MSCs) that are designed to deliver protective molecules to modulate inflammation and promote tissue repair. The therapy is being investigated for several inflammatory and autoimmune conditions, including Graft Versus Host Disease (GVHD), Chronic Kidney Disease (CKD), Type 1 and Type 2 Diabetes, and acute lung indications. It is currently in Phase 1/2 clinical development for GVHD, with other indications in the IND-enabling stage.
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