Drug intelligence / Profile preview

RelaxPLX

Development stage
Unknown
Lead developer
Monteloeder
Modality
Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

RelaxPLX is a proprietary botanical dietary supplement ingredient derived from lemon verbena (*Lippia citriodora*) leaves, developed by the nutraceutical company Monteloeder. It is standardized to contain high concentrations of verbascoside (≥24%) and total phenylpropanoids (≥28%). The extract acts as a positive allosteric modulator of GABA-A receptors in the central nervous system, enhancing the inhibitory effects of GABA to manage stress, anxiety, and sleep disorders. Clinical trials have demonstrated its efficacy in reducing perceived stress, lowering cortisol levels, and improving sleep quality without the adverse effects typically associated with benzodiazepines.

Brand names
RelaxPLX
Other names
lemon verbena extractLippia citriodora extract
02

Targets

GABAA (Gamma-aminobutyric acid receptor)

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