Drug intelligence / Profile preview

Relivyx Plus

Development stage
Approved
Modality
Small Molecules
Administration
Topical
01

Overview

Relivyx Plus is a prescription topical pain-relief combination kit that contains **lidocaine 5% patches** and a **menthol roll-on gel**. The product is a **small-molecule combination** intended for local analgesia, with lidocaine acting primarily as a blocker of voltage-gated sodium channels in peripheral nerves to reduce initiation and conduction of pain signals, while menthol provides topical counterirritant and cooling analgesic effects that are generally mediated through sensory nerve modulation. Available information indicates the lidocaine patch component contains 700 mg lidocaine in an adhesive matrix on a polyester felt backing. Public labeling indicates the product is marked **Rx Only**, but also states that it has **not been found by FDA to be safe and effective** and that the labeling has **not been approved by FDA**, consistent with an unapproved drug product. A specific sponsoring developer or manufacturer is not clearly identifiable from the provided information.

Brand names
Relivyx Plus
Other names
Relivyx Pluslidocaine + menthol
02

Targets

NaV (Voltage-gated sodium channels)

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