Drug intelligence / Profile preview

Remedril

Development stage
Phase 3
Lead developer
Remed Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

**Remedril** is an oral fixed-dose combination of phenylephrine hydrochloride and brompheniramine maleate marketed by Remed Pharmaceuticals for symptomatic management of upper-respiratory allergic and cold symptoms. Phenylephrine is a direct alpha-1 adrenergic receptor agonist that constricts nasal mucosal blood vessels to reduce congestion, while brompheniramine is a sedating first-generation histamine H1 receptor antagonist that reduces histamine-mediated sneezing, rhinorrhea, itching, and watery eyes. The product is supplied as syrup and oral drops and is indicated for common colds, allergic rhinitis, and sinusitis.

Brand names
Remedril
Other names
brompheniramine maleate + phenylephrine hydrochloridephenylephrine hydrochloride + brompheniramine maleate
02

Targets

HRH1 (Histamine H1 Receptor)ADRA1A (α1A)

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