Drug intelligence / Profile preview

remifentanil + propofol + desflurane

Development stage
Phase 4
Lead developer
Abbott
Modality
Small Molecules
Administration
Intravenous, Inhalation
01

Overview

A balanced anesthesia combination used for induction and maintenance of general anesthesia during surgical procedures. This combination leverages remifentanil (an ultra-short-acting μ-opioid receptor agonist), propofol (an intravenous anesthetic), and desflurane (an inhalational anesthetic) to provide effective anesthesia with rapid recovery characteristics and hemodynamic stability.

02

Targets

GABA-B (Gamma-aminobutyric acid receptor type B)GRIA1 (AMPA receptor subunit GluA1)GLRA1 (Glycine receptor subunit Alpha-1)MOR (Mu opioid receptor)KCNA1 (Voltage-gated potassium channel subfamily A member 1)

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