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remifentanil + remimazolam is an investigational anesthesia combination regimen being evaluated by Yonsei University for total intravenous anesthesia (TIVA). This regimen combines remifentanil, an ultra-short-acting mu-opioid receptor agonist that provides potent analgesia, with remimazolam, a short-acting benzodiazepine that acts as a GABA-A receptor positive allosteric modulator to induce sedation. The combination is specifically being studied in the context of laparoscopic-assisted gastrectomy for patients with stomach neoplasms (gastric cancer) to assess its impact on postoperative pain and recovery compared to other opioid-sedative combinations like sufentanil-remimazolam.
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