Drug intelligence / Profile preview

Remura

Development stage
Unknown
Lead developer
Bausch + Lomb
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Remura is a bromfenac-based ophthalmic solution developed by ISTA Pharmaceuticals as a topical nonsteroidal anti-inflammatory drug (NSAID) for the treatment of dry eye disease, formulated to reduce ocular inflammation and associated signs and symptoms of dry eye through inhibition of cyclooxygenase (COX) enzymes and suppression of prostaglandin synthesis on the ocular surface.[6][12][14] It was evaluated in a Phase 3 clinical program in patients with dry eye disease, comparing multiple bromfenac concentrations against placebo for improvements in clinical signs and patient-reported symptoms.[6][12][14]

Brand names
Remura
Other names
Remura bromfenac ophthalmic solution for dry eye
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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