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RENALIT-COMBI is a dietary supplement (integratore alimentare) developed and marketed by the Italian company Bio-STILOGIT Pharmaceuticals. It is specifically formulated for the management and prevention of renal lithiasis (kidney stones) and the maintenance of urinary tract health. The product contains a combination of potassium citrate, magnesium citrate, and an extract of *Phyllanthus niruri* (commonly known as "stone breaker"). The citrate salts function as urinary alkalinizers and inhibitors of calcium stone formation by increasing urinary pH and complexing with calcium ions, which reduces the supersaturation of calcium oxalate and phosphate. *Phyllanthus niruri* is included for its anti-lithogenic properties, which include interfering with the early stages of stone formation and aggregation, as well as providing antispasmodic effects on the urinary tract to facilitate the expulsion of calculi.
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