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RENALIT-COMBI COLIC is a dietary supplement developed by Bio-STILOGIT Pharmaceuticals, primarily marketed in Italy for the management of nephrolithiasis (kidney stones) and the relief of renal colic. The formulation typically combines potassium citrate and magnesium citrate with the botanical extract *Phyllanthus niruri*. The citrate components serve as urinary alkalinizers and inhibitors of calcium stone formation by increasing urinary pH and sequestering calcium ions into soluble complexes. *Phyllanthus niruri*, often referred to as stone breaker, is included for its potential litholytic effects and its ability to relax urinary tract smooth muscle, which facilitates the passage of stones and reduces the pain associated with colic episodes. The product is sold as a retail consumer health product and is not classified as a prescription pharmaceutical.
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