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Renhaim personalized neoantigen cancer vaccine

Development stage
Preclinical
Lead developer
Renhaim
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

Renhaim's personalized neoantigen cancer vaccine is an mRNA-based immunotherapy designed to treat various cancers by targeting patient-specific tumor neoantigens. The vaccine utilizes mRNA technology to encode unique mutations (neoantigens) identified from a patient's own tumor through genomic sequencing. Once administered, the mRNA is translated into neoantigenic proteins within the patient's cells, which are then processed and presented to the immune system. This process is intended to provoke a robust and individualized anti-tumor T-cell response, allowing the immune system to recognize and eliminate cancer cells expressing those specific mutations. The program is currently in the preclinical/research stage of development.

Other names
Personalized Neoantigen Cancer VaccineRenhaim-patient-specific tumor neoantigens-mRNA cancer vaccine (personalized)-Cancer (general/personalized per patient)
02

Targets

Patient-specific tumor neoantigen-HLA complex

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