Drug intelligence / Profile preview

Replikin-based Taura Syndrome vaccine

Development stage
Preclinical
Lead developer
Replikins
Modality
Peptides, Vaccines & Immunotherapeutics
Administration
Intramuscular, Oral
01

Overview

The Replikin-based Taura Syndrome vaccine is a synthetic peptide vaccine developed by Replikins LLC to protect shrimp, specifically *Litopenaeus vannamei*, against the Taura Syndrome Virus (TSV). The vaccine technology is based on the identification of 'Replikins,' which are specific, conserved peptide sequences within viral proteins characterized by a high concentration of lysine and histidine residues. These sequences are identified using proprietary algorithms that correlate Replikin concentration with viral replication and outbreak cycles. By synthesizing these specific peptides and administering them to shrimp, the vaccine aims to stimulate the invertebrate innate immune system to recognize and neutralize TSV. Research and trials have indicated that administration of these synthetic peptides can significantly increase survival rates in shrimp populations exposed to the virus, offering a potential solution for a major pathogen in the aquaculture industry.

Other names
Taura Syndrome Replikin vaccineTSV Replikin vaccineSynthetic Replikin peptide vaccine for Taura Syndrome
02

Targets

Taura syndrome virus polyprotein

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