Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Restorative Microbiota Therapy
- Development stage
- Phase 2
- Lead developer
- University of Minnesota
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral, Rectal, Intracolonic, Nasogastric, Nasoduodenal
01
Overview
Restorative Microbiota Therapy (RMT) is an investigational live biotherapeutic product consisting of a standardized, oral, encapsulated formulation of freeze-dried microbiota derived from healthy, screened human donors. [5, 6] It is designed to restore a healthy gut microbiome composition. [4] It is being studied to determine if modulating the gut microbiome can enhance the efficacy of cancer treatments, particularly the combination of immune checkpoint inhibitors and chemotherapy. [12] The product described in the provided context was manufactured by the University of Minnesota's Microbiota Therapeutics Program for a clinical trial in patients with advanced Non-Small Cell Lung Cancer (NSCLC). [3, 12]
- Other names
- Fecal Microbiota TransplantFMTMicrobiota Transplant TherapyMTTIntestinal Microbiota TransplantationIMT
Beyond the preview
Go deeper on Restorative Microbiota Therapy.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Restorative Microbiota Therapy.