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Restylane Shaype
- Development stage
- Unknown
- Lead developer
- Galderma
- Modality
- Recombinant Proteins and Enzymes, Small Molecules, Hydrogel Systems → Drug Delivery Systems
- Administration
- Subcutaneous
01
Overview
Restylane Shaype is an injectable, sterile, transparent, biodegradable gel composed of non-animal crosslinked sodium hyaluronate (hyaluronic acid) with the addition of lidocaine hydrochloride. It is specifically designed for temporary augmentation and shaping of the chin region and lower face. Utilizing NASHA HD technology, it is the firmest hyaluronic acid filler in the Restylane portfolio and provides a bone-mimicking effect when injected deeply onto bone (supraperiosteal layer). This high-density gel offers strong mechanical support for tissue projection and contouring, allowing precise enhancement of chin definition and jawline structure without surgery. The effects are long-lasting—up to 12 months—and reversible. Developed by Galderma with input from leading experts in facial aesthetics, it addresses unmet needs for non-surgical chin augmentation with natural-looking results[1][2][3][5][7].
- Brand names
- Restylane Shaype
- Other names
- Restylane SHAYPERestylane® SHAYPE™SHAYPE
02
Targets
NaV (Voltage-gated sodium channels)CD44 (CD44 antigen)RHAMM (Hyaluronan-mediated motility receptor)
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