Drug intelligence / Profile preview

resveravine

Development stage
Unknown
Lead developer
Nexira
Modality
Small Molecules
Administration
Oral
01

Overview

Resveravine is a standardized natural extract derived from the stems of the grapevine (*Vitis vinifera L.*), developed by the French company Nexira. It is characterized by a high concentration of oligostilbenes, specifically containing 20% active components including trans-resveratrol and ε-viniferin. As a nutraceutical ingredient, it functions primarily as an antioxidant and anti-aging compound by targeting the SIRT-1 (sirtuin-1) gene, which plays a critical role in longevity and metabolic regulation. Resveravine is marketed for use in dietary supplements to support cardiovascular health, provide anti-inflammatory effects, and promote healthy aging. It is chemically distinct from simple resveratrol extracts due to its specific profile of grapevine-derived stilbenoids.

Brand names
Resveravine
Other names
Vitis vinifera extractGrapevine stem extract
02

Targets

NQO2 (Ribosyldihydronicotinamide dehydrogenase [quinone])SIRT1 (NAD-dependent protein deacetylase sirtuin-1)

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