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Retinoin
- Development stage
- Unknown
- Lead developer
- Topix Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Topical, Transdermal
01
Overview
**Retinoin** is a Topix Pharmaceuticals physician-dispensed topical retinol skincare formulation and patented-brand delivery platform for age-defense skincare. Its patent-pending transdermal delivery system is intended to promote rapid skin retinization while reducing the irritation often associated with topical retinoids; Topix states that the formulation is coupled with bakuchiol, licorice root, and green tea polyphenols for age-defying and skin-soothing effects. The retinol component is expected to act after metabolic conversion to retinoic acid, activating retinoic acid receptor signaling involved in epidermal differentiation, keratinocyte turnover, and dermal collagen remodeling. ([topixpharm.com](https://topixpharm.com/science/))
- Brand names
- Retinoin
02
Targets
RARA (Retinoic acid receptor alpha)RARB (Retinoic acid receptor beta)RARG (Retinoic acid receptor gamma)RXRA (Retinoid X receptor alpha)
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