Drug intelligence / Profile preview

REVERSAL

Development stage
Unknown
Lead developer
Koru Pharmaceuticals
Modality
Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Subcutaneous, Intradermal
01

Overview

REVERSAL is a family of injectable biostimulators developed by Koru Pharmaceuticals for aesthetic skin and soft-tissue rejuvenation. The product line includes the original REVERSAL (a hybrid of polylactic acid and hyaluronic acid), REVERSAL Neo (high-purity PLLA), and REVERSAL Dual (a dual-vial PLLA and HA system). These products function by inducing a controlled biological response that stimulates fibroblasts to produce endogenous collagen, leading to improved skin elasticity, volume restoration, and wrinkle reduction. The inclusion of hyaluronic acid provides immediate hydration and volumization, while the polylactic acid component ensures long-term structural improvement through tissue regeneration.

Brand names
REVERSALREVERSAL NeoREVERSAL Dual

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