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**Reynoutria extract** most commonly refers to a botanical extract prepared from *Reynoutria japonica* root or rhizome, also known as Japanese knotweed and historically as *Polygonum cuspidatum* or *Fallopia japonica*. In commercial human-use products it is typically marketed as a dietary supplement or nutraceutical and is often standardized for **trans-resveratrol**, with additional polyphenols such as emodin and related stilbenes/anthraquinones contributing to its pharmacology. Its biological activity is **multitarget and nonspecific** rather than that of a single defined pharmaceutical mechanism; reported effects include antioxidant, anti-inflammatory, and signaling-modulatory actions, but there is no single established approved drug mechanism or single validated therapeutic target for a product named simply \"reynoutria extract\". The term can also be used more broadly for extracts from other *Reynoutria* species, so the exact substance depends on source plant, plant part, extraction method, and standardization profile.
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