Drug intelligence / Profile preview

reynoutria extract

Development stage
Unknown
Administration
Oral
01

Overview

**Reynoutria extract** most commonly refers to a botanical extract prepared from *Reynoutria japonica* root or rhizome, also known as Japanese knotweed and historically as *Polygonum cuspidatum* or *Fallopia japonica*. In commercial human-use products it is typically marketed as a dietary supplement or nutraceutical and is often standardized for **trans-resveratrol**, with additional polyphenols such as emodin and related stilbenes/anthraquinones contributing to its pharmacology. Its biological activity is **multitarget and nonspecific** rather than that of a single defined pharmaceutical mechanism; reported effects include antioxidant, anti-inflammatory, and signaling-modulatory actions, but there is no single established approved drug mechanism or single validated therapeutic target for a product named simply \"reynoutria extract\". The term can also be used more broadly for extracts from other *Reynoutria* species, so the exact substance depends on source plant, plant part, extraction method, and standardization profile.

Other names
Japanese knotweed extractPolygonum cuspidatum extractReynoutria japonica extractFallopia japonica extract
02

Targets

TYR (Tyrosinase)MMP12 (Macrophage Metalloelastase)ButyrylcholinesteraseAcetylcholinesteraseElastaseHYAL (Hyaluronidase family (HYAL))

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