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RG-19 HIGH-PRO

Development stage: Preclinical
Lead developer: Hangzhou Ronggu Biotechnology
Modality: CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies
Administration: Intravenous

Overview

RG-19 HIGH-PRO is a preclinical-stage chimeric antigen receptor natural killer (CAR-NK) cell therapy being developed by Hangzhou RonGu Biotechnology for the treatment of gastric cancer. The therapy utilizes a lentivirus-based nanobody co-expression CAR platform to engineer cord blood-derived NK cells to target CD19-expressing tumor cells. By co-expressing a nanobody-based CAR, the product is designed to enhance tumor-killing efficacy and infiltration into solid tumors, specifically targeting gastric cancer cells.

Targets

CD19 (B lymphocyte antigen CD19)

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