Drug intelligence / Profile preview

RG-CMH

Development stage
Preclinical
Lead developer
Medigreen Biotechnology
Administration
Oral
01

Overview

**RG-CMH** is an oral Chinese medicinal herb complex evaluated as supportive care for breast cancer patients receiving chemotherapy or radiotherapy. Each capsule contained rose geranium powder plus aqueous extracts of *Angelica sinensis*, *Codonopsis pilosula*, and *Ganoderma tsugae*; the preparation was standardized by ferulic-acid content. In a randomized, double-blind, placebo-controlled 6-week study, RG-CMH was associated with smaller decreases in leukocyte and neutrophil counts than placebo, although it did not significantly improve lymphocyte-subset counts or treatment-related toxicities. Its molecular mechanism is not established; the intended activity is broad immunomodulatory and hematologic support during cytotoxic cancer treatment. ([cambridge.org](https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/effects-of-a-chinese-medical-herbs-complex-on-cellular-immunity-and-toxicityrelated-conditions-of-breast-cancer-patients/ABBCA3B62D1AD0D963A293FB1D788A70))

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