Drug intelligence / Profile preview

rhGM-CSF gel

Development stage
Phase 4
Lead developer
Partner Therapeutics
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

rhGM-CSF gel is a topical pharmaceutical formulation containing recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF). It is primarily used to promote wound healing, particularly for deep second-degree burns and chronic skin ulcers such as pressure ulcers, venous ulcers, and diabetic foot ulcers. The active ingredient, rhGM-CSF, functions as a cytokine that stimulates the production, proliferation, and differentiation of granulocytes and macrophages. By modulating the biological properties of these immune cells during the inflammation phase, it accelerates wound repair, facilitates angiogenesis (formation of new blood vessels), promotes re-epithelialization, and enhances the growth of granulation tissue, contributing to infection control and overall wound closure.

Brand names
Yi FuJinlei
Other names
重组人粒细胞巨噬细胞刺激因子凝胶Human Granulocyte/Macrophage Colony-stimulating Factor Gel for External Use
02

Targets

CSF2R (Granulocyte-macrophage colony-stimulating factor receptor)

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