Drug intelligence / Profile preview

rHIgM12B7

Development stage
Phase 1
Lead developer
Mayo Clinic
Modality
Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

rHIgM12B7 is a recombinant form of the monoclonal IgM antibody M12 isolated from a Waldenstrom macroglobulinaemia patient with potential immunomodulating activity. It functions as a B7-DC cross-linking agent, targeting programmed cell death 1 ligand 2.

Other names
B7-DC cross-linking antibody rHIgM12B7B-7-DC cross-linking antibody rHIgM12B7B 7-DC cross-linking antibody rHIgM12B7recombinant form of the monoclonal IgM antibody M12
02

Targets

PDCD1LG2 (Programmed cell death 1 ligand 2)

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