Drug intelligence / Profile preview

rhinovirus-targeted nasal spray

Development stage
Preclinical
Lead developer
Applied Biological Laboratories
Modality
Recombinant Proteins and Enzymes
Administration
Intranasal
01

Overview

Applied Biological Laboratories is developing an intranasal rhinovirus-targeted treatment composed of a soluble intercellular adhesion molecule 1 competitive inhibitor approach together with immune-modulating proteins. The spray is intended to prevent or reduce rhinovirus infection by competitively blocking viral attachment at the rhinovirus receptor-binding site while enhancing local innate mucosal antiviral responses. The program is described as IND-enabling for rhinovirus infection and the common cold.

Other names
Rhinovirus-targeted nasal spray (competitive inhibitor + immune-modulating proteins)rhinovirus-targeted nasal spraysICAM-1 targeted nasal spraysICAM1 targeted nasal spraysICAM 1 targeted nasal spray

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