Drug intelligence / Profile preview

rhizoma acori tatarinowii

Development stage
Preclinical
Administration
Oral
01

Overview

Rhizoma Acori Tatarinowii, commonly known as Shi Chang Pu, is a traditional Chinese medicinal herb derived from the dried rhizome of the Acorus tatarinowii plant. It has a fragrant aroma and a bitter, slightly pungent taste. The herb is primarily used to open orifices, vaporize phlegm, calm the spirit, disperse wind and transform turbid dampness. It acts on the heart, spleen and stomach meridians with warm, pungent and bitter properties. Pharmacologically, it has sedative effects due to its volatile oils (notably α-asarone and β-asarone), which help treat restlessness and unconsciousness. It also promotes digestion by resolving dampness in the middle energizer (digestive system), harmonizes stomach function to relieve epigastric fullness and pain caused by Qi disorder or dampness accumulation. Additionally, it calms the heart to induce tranquilization useful for insomnia and amnesia when combined with other herbs. The herb contains diverse phytochemicals including phenylpropanoids (major constituents α- and β-asarone), sesquiterpenes, lignans, flavonoids, alkaloids, amides and organic acids contributing to its pharmacological activities such as antimicrobial effects and potential anti-cancer activity observed in some studies. It is traditionally administered as decoctions (5-10g dose) or in powder/pill form[1][2][3][4][6][7].

Other names
Sweetflag RhizomeGrassleaf Sweetflag RhizomeRock Sweetflag RootAcori Tatarinowii Rhizoma石菖蒲
02

Targets

PPARG (Peroxisome proliferator-activated receptor gamma)PPARA (Peroxisome proliferator-activated receptor alpha)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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