rhizoma arisaemetis preparata

Rhizoma Arisaemetis Preparata, known in Traditional Chinese Medicine (TCM) as **Zhi Tian Nan Xing**, is a processed herbal preparation derived from the tubers of *Arisaema* species, such as *Arisaema erubescens*, *Arisaema heterophyllum*, or *Arisaema amurense*. The raw herb is naturally toxic and acrid; therefore, it is typically processed with ginger juice and alum to mitigate toxicity and enhance its therapeutic properties. In clinical research, particularly in China, it is being investigated for transvaginal administration to treat persistent high-risk human papillomavirus (HPV) infections and associated lesions like cervical intraepithelial neoplasia (CIN) and vaginal intraepithelial neoplasia (VaIN). Its mechanism of action is thought to involve the induction of apoptosis in HPV-infected cells and the modulation of the local immune microenvironment, although specific molecular targets are not fully characterized in standard Western pharmacology.

Other names

制天南星Zhi Tian Nan Xingprocessed Arisaema tuberRhizoma Arisaematis PreparatumRhizoma Arisaematis Preparata