Drug intelligence / Profile preview

rhodiola rosea extract

Development stage
Unknown
Lead developer
Schwabe
Administration
Oral
01

Overview

Vitango is a traditional herbal medicinal product containing a standardized dry extract of *Rhodiola rosea* (WS 1375). Developed by Schwabe Pharmaceuticals, it is indicated for the temporary relief of symptoms associated with stress, such as fatigue, exhaustion, and irritability. As an adaptogen, it is thought to enhance the body's resistance to stress by modulating the hypothalamic-pituitary-adrenal (HPA) axis and regulating the release of stress hormones like cortisol. It also influences monoaminergic neurotransmitter levels (serotonin, dopamine, and norepinephrine) and induces the expression of heat shock proteins (HSP70) to protect cells from stress-induced damage.

Brand names
Vitango
Other names
Arctic root extractGolden root extractRoseroot extractWS 1375WS1375WS-1375
02

Targets

CYP2D6 (Cytochrome P450 2D6)CYP2C9 (Cytochrome P450 family 2 subfamily C member 9)CYP3A4 (Cytochrome P450 3A4)CYP1A2 (Cytochrome P450 1A2)MAOB (Monoamine oxidase B)MAOA (Monoamine oxidase A)CYP2C19 (Cytochrome P450 2C19)

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