Drug intelligence / Profile preview

Rhumalgan

Development stage
Unknown
Lead developer
Lagap
Modality
Small Molecules
Administration
Oral, Rectal, Topical
01

Overview

Rhumalgan is a branded generic formulation of diclofenac, a potent non-steroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic, and anti-inflammatory properties. Developed by Lagap, Rhumalgan is available in various formulations, including oral tablets (Rhumalgan CR, SR, XL, and enteric-coated), powder for oral solution (Rhumalgan K), rectal suppositories (Rhumalgan Retard), and a topical gel (Rhumalgan Emulgel). It works by reversibly inhibiting the cyclooxygenase enzymes COX-1 and COX-2, thereby blocking the synthesis of prostaglandins that mediate pain, fever, and inflammation. Rhumalgan is approved for the treatment of acute and chronic pain and inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, dysmenorrhea, migraine, and musculoskeletal injuries.

Brand names
RhumalganRhumalgan CRRhumalgan EmulgelRhumalgan KRhumalgan RetardRhumalgan SRRhumalgan XL
Other names
diclofenacdiclofenac potassiumdiclofenac sodium
02

Targets

15-LOX (Lysyl Oxidase)PPARG (Peroxisome proliferator-activated receptor gamma)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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