Drug intelligence / Profile preview

rhus coriaria phenolic fraction

Development stage
Preclinical
Administration
Oral
01

Overview

*Rhus coriaria* phenolic fraction is a botanical extract derived from the fruit of the sumac plant (*Rhus coriaria*), specifically enriched for its phenolic constituents. In preclinical studies, this fraction has demonstrated potent antihyperlipidemic and hepatoprotective effects, significantly improving lipid profiles by lowering total cholesterol, triglycerides, and LDL while increasing HDL levels. Its mechanism of action is attributed to its strong antioxidant and anti-inflammatory properties, which include the reduction of oxidative stress markers like malondialdehyde and the restoration of endogenous antioxidants such as glutathione. Additionally, it has been shown to mitigate liver damage by reducing elevated levels of hepatic enzymes such as alanine transaminase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP).

Other names
phenolic components of Iraqi sumacphenolic constituents of Rhus coriariasumac phenolic fraction
02

Targets

ALPL (Tissue-nonspecific alkaline phosphatase)GSH (Glutathione)AST (Glutamate oxaloacetate transaminase 1)

Beyond the preview

Go deeper on rhus coriaria phenolic fraction.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on rhus coriaria phenolic fraction.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call